This suggests that the roles of the cytoskeleton in cybernetic or cognitive functions cannot be discounted in fact, they should be researched further to see if their transductance abilities are used to fill the role of “wires” in neural circuitry. The central role of cytoskeletal filaments and MT in determining nerve fiber morphology indirectly affects the processing of all electrical impulses handled by neurons. Because of the twisting and bending capabilities of microtubules, the direction of neurite growth, or its navigation, can be assisted by the internal mechanisms of the MAPs dynein and kinesin. As quickly as organelles such as ER can synthesize dimers and oligomers for IF and MT, the filaments grow or extend and push the elastic membranes outward. The main internal process in neurite cytoskeletal formation is polymerization. Internal factors that limit the extension of neurites are primarily associated with the time required to build the cytoskeleton (blue line in the illustration) of the new appendage. Internal and external factors govern the sprouting and growth of neurites. Understanding Context Cross-ReferenceĬlick on these Links to other posts and glossary/bibliography references adjusting the weights of existing links (synapses) andĪ long-term memory model should reflect the ability of our brains to form new links throughout our lifetime.using relay cells to form links with remote cells.The physiology of the brain can support learning by… It may, however, be possible to logically simulate link formation with a physically static net. In those networks, only the weights change as a result of learning. This differs profoundly from typical artificial neural networks whose link structure is static before learning begins. Typical artificial neural networks model learning by adjusting the weights (usually through backpropagation) of existing links instead of forming new ones.Ī neuromorphic model for computation that accounts for the brain’s ability to form new – and retract existing – physical links would be a dynamic network capable of adapting or learning by forming new links. If nerve fibers stopped forming early in life, link formation would not be critical to learning. We also know they can be retracted as well as extended. Due to improved imaging resolutions and preparation techniques, we now know that axon termini, dendrites, and spines form throughout our lifetime. It was once believed that the link structure of the nervous system was formed randomly during embryogenesis and remained static after maturation – sometime between early development and adolescence (except for regeneration after injury).
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